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KMID : 1103920140200020204
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Korean Journal of Hepatology
2014 Volume.20 No. 2 p.204 ~ p.207
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Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A
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Chang Hyo-Jeong
Sinn Dong-Hyun
Cho Sung-Gyun
Oh Tae-Hoon
Jeon Tae-Joo
Shin Won-Chang
Choi Won-Choong
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Abstract
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Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-yearold female with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinical course. A diagnostic workup revealed AIHA and PRCA as the cause of the anemia. The patient was treated with an initial transfusion and corticosteroid therapy. Her anemia and liver function test were completely recovered by 9 months after the initial presentation. We review the clinical features and therapeutic strategies for this rare case of extrahepatic manifestation of AHA.
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KEYWORD
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Hepatitis A, Pure red-cell aplasia, Autoimmune hemolytic anemia
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